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Tumor-penetrating Peptide for Systemic Targeting of Tenascin-C
Lingasamy P, Tobi A, Kurm K, Kopanchuk S, Sudakov A, Salumäe M, Rätsep T, Asser T, Bjerkvig R, Teesalu T.
Sci Rep. 2020 Apr 2;10(1):5809. doi: 10.1038/s41598-020-62760-y. PMID: 32242067
A Novel CNS-homing Peptide for Targeting Neuroinflammatory Lesions in Experimental Autoimmune Encephalomyelitis
Acharya B, Meka RR, Venkatesha SH, Lees JR, Teesalu T, Moudgil KD.
Mol Cell Probes. 2020 Jun;51:101530. doi: 10.1016/j.mcp.2020.101530. Epub 2020 Feb 5. PMID: 32035108
Dual-peptide Functionalized Acetalated Dextran-Based Nanoparticles for Sequential Targeting of Macrophages During Myocardial Infarction
Torrieri G, Fontana F, Figueiredo P, Liu Z, Ferreira MPA, Talman V, Martins JP, Fusciello M, Moslova K, Teesalu T, Cerullo V, Hirvonen J, Ruskoaho H, Balasubramanian V, Santos HA.
Nanoscale. 2020 Jan 28;12(4):2350-2358. doi: 10.1039/c9nr09934d. Epub 2020 Jan 13. PMID: 31930241
Hierarchical Nanostructuring of Porous Silicon With Electrochemical and Regenerative Electroless Etching
Mäkilä E, Anton Willmore AM, Yu H, Irri M, Aindow M, Teesalu T, Canham LT, Kolasinski KW, Salonen J.
ACS Nano. 2019 Nov 26;13(11):13056-13064. doi: 10.1021/acsnano.9b05740. Epub 2019 Nov
Bi-specific tenascin-C and fibronectin targeted peptide for solid tumor delivery
Lingasamy P, Tobi A, Haugas M, Hunt H, Paiste P, Asser T, Rätsep T, Kotamraju VR, Bjerkvig R, Teesalu T.
Biomaterials. 2019 Oct;219:119373. doi: 10.1016/j.biomaterials.2019.119373. Epub 2019 Jul 19.
Peptide-guided nanoparticles for glioblastoma targeting
Säälik P, Lingasamy P, Toome K, Mastandrea I, Rousso-Noori L, Tobi A, Simón-Gracia L, Hunt H, Paiste P, Kotamraju VR, Bergers G, Asser T, Rätsep T, Ruoslahti E, Bjerkvig R, Friedmann-Morvinski D, Teesalu T.
J Control Release. 2019 Jun 27. pii: S0168-3659(19)30328-1. doi: 10.1016/j.jconrel.2019.06.018. [Epub ahead of print].
IGF signalling and endocytosis in the human villous placenta in early pregnancy as revealed by comparing quantum dot conjugates with a soluble ligand
Karolczak-Bayatti M, Forbes K, Horn J, Teesalu T, Harris LK, Westwood M, Aplin JD.
Nanoscale. 2019 Jun 27;11(25):12285-12295. doi: 10.1039/c8nr10337b.
Phage-Display-Derived Peptide Binds to Human CD206 and Modeling Reveals a New Binding Site on the Receptor
Asciutto EK, Kopanchuk S, Lepland A, Simón-Gracia L, Aleman C, Teesalu T, Scodeller P
J Phys Chem B, 2019 Mar 7;123(9):1973-1982. doi: 10.1021/acs.jpcb.8b11876. Epub 2019 Feb 27.
Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy
Hussain S, Joo J, Kang J, Kim B, Braun GB, She ZG, Kim D, Mann AP, Mölder T, Teesalu T, Carnazza S, Guglielmino S, Sailor MJ, Ruoslahti E..
Nat Biomed Eng. 2018 Feb;2(2):95-103. doi: 10.1038/s41551-017-0187-5. Epub 2018 Jan 22.
Peritoneal Carcinomatosis Targeting with Tumor Homing Peptides
Simón-Gracia L, Hunt H, Teesalu T..
Molecules. 2018 May 16;23(5). pii: E1190. doi: 10.3390/molecules23051190. Review.
Application of polymersomes engineered to target p32 protein for detection of small breast tumors in mice
Simón-Gracia L, Scodeller P, Fuentes SS, Vallejo VG, Ríos X, San Sebastián E, Sidorenko V, Di Silvio D, Suck M, De Lorenzi F, Rizzo LY, von Stillfried S, Kilk K, Lammers T, Moya SE, Teesalu T.
Oncotarget. 2018 Apr 10;9(27):18682-18697. doi: 10.18632/oncotarget.24588. eCollection 2018 Apr 10.
Competition of charge-mediated and specific binding by peptide-tagged cationic liposome-DNA nanoparticles in vitro and in vivo
Wonder E, Simón-Gracia L, Scodeller P, Majzoub RN, Kotamraju VR, Ewert KK, Teesalu T, Safinya CR.
Biomaterials. 2018 Jun;166:52-63. doi: 10.1016/j.biomaterials.2018.02.052. Epub 2018 Mar 2.
Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease
Mann AP, Scodeller P, Hussain S, Braun GB, Mölder T, Toome K, Ambasudhan R, Teesalu T, Lipton SA, Ruoslahti E.
Nat Commun. 2017 Nov 10;8(1):1403. doi: 10.1038/s41467-017-01096-0.
Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide
Scodeller P, Simón-Gracia L, Kopanchuk S, Tobi A, Kilk K, Säälik P, Kurm K, Squadrito ML, Kotamraju VR, Rinken A, De Palma M, Ruoslahti E, Teesalu T.
Sci Rep. 2017 Nov 7;7(1):14655. doi: 10.1038/s41598-017-14709-x.
Selective Targeting of a Novel Vasodilator to the Uterine Vasculature to Treat Impaired Uteroplacental Perfusion in Pregnancy
Cureton N, Korotkova I, Baker B, Greenwood S, Wareing M, Kotamraju VR, Teesalu T, Cellesi F, Tirelli N, Ruoslahti E, Aplin JD, Harris LK.
Theranostics. 2017 Aug 29;7(15):3715-3731. doi: 10.7150/thno.19678. eCollection 2017.
Vascular changes in tumors resistant to a vascular disrupting nanoparticle treatment.
Sharma S, Mann AP, Mölder T, Kotamraju VR, Mattrey R, Teesalu T, Ruoslahti E.
J Control Release. 2017 Oct 13;268:49-56. doi: 10.1016/j.jconrel.2017.10.006. [Epub ahead of print]
Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles
Hunt H, Simón-Gracia L, Tobi A, Kotamraju VR, Sharma S, Nigul M, Sugahara KN, Ruoslahti E, Teesalu T.
J Control Release. 2017 Aug 28;260:142-153. doi: 10.1016/j.jconrel.2017.06.005. Epub 2017 Jun 8.
Ratiometric in vivo auditioning of targeted silver nanoparticles
Toome K, Willmore AA; Paiste P, Tobi A, Sugahara KN, Kirsimäe K, Ruoslahti E, Braun GB, Teesalu T.
Nanoscale. 2017 Jul 20;9(28):10094-10100. doi: 10.1039/c7nr04056c.
Hyaluronan-binding peptide for targeting peritoneal carcinomatosis
Ikemoto H, Lingasamy P, Anton Willmore AM, Hunt H, Kurm K, Tammik O, Scodeller P, Simón-Gracia L, Kotamraju VR, Lowy AM, Sugahara KN, Teesalu T.
Tumour Biol. 2017 May;39(5):1010428317701628. doi: 10.1177/1010428317701628.
Tumor-Penetrating Nanosystem Strongly Suppresses Breast Tumor Growth
Sharma S, Kotamraju VR, Mölder T, Tobi A, Teesalu T, Ruoslahti E.
Nano Lett. 2017 Mar 8;17(3):1356-1364. doi: 10.1021/acs.nanolett.6b03815. Epub 2017 Feb 17.
iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes
Simon-Gracia L, Hunt H, Scodeller P, Gaitzsch J, Kotamraju VR, Sugahara KN, Tammik O, Ruoslahti E, Battaglia G,Teesalu T
Biomaterials. 2016 Jul 20;104:247-257. doi: 10.1016/j.biomaterials.2016.07.023. [Epub ahead of print]
A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
Aman P. Mann, Pablo Scodeller, Sazid Hussain, Jinmyoung Joo, Ester Kwon, Gary B. Braun, Tarmo Mölder, Zhi-gang She, Venkata Ramana Kotamraju, Barbara Ranscht, Stan rajewski, Tambet Teesalu, Sangeeta Bhatia, Michael J. Sailor, Erkki Ruoslahti.
Nature Communications 7, Article number: 11980, doi: 10.1038/ncomms11980
Tumor-homing peptides as tools for targeted delivery of payloads to the placenta
King A, Ndifon C, Lui S, Widdows K, Kotamraju VR, Agemy L, Teesalu T, Glazier JD, Cellesi F, Tireli N, Aplin JD, Ruoslahti E, Harris LK.
Science Advances 06 May 2016: Vol. 2, no. 5, e1600349 DOI: 10.1126/sciadv.1600349
Paclitaxel-loaded Polymersomes for Enhanced Intraperitoneal Chemotherapy
Simón-Gracia L,Hunt H, Scodeller PD, Gaitzsch J, Braun GB, Willmore AA, Ruoslahti E, Battaglia G, Teesalu T
Mol Cancer Ther. 2016 Feb 15. pii:molcanther.0713.2015 [Epub ahead of print]
Urokinase-controlled tumor penetrating peptide
Braun GB, Sugahara KN, Yu OM, Kotamraju VR, Mölder T, Lowy AM, Ruoslahti E, Teesalu T
J Control Release. 2016 Apr 19. pii: S0168-3659(16)30240-1. doi: 10.1016/j.jconrel.2016.04.027. [Epub ahead of print]
New p32/gC1qR Ligands for Targeted Tumor Drug Delivery
Paasonen L,Sharma S, Braun GB, Kotamraju VR, Chung TD, She ZG, Sugahara KN, Yliperttula M, Wu B, Pellecchia M, Ruoslahti E, Teesalu T
Chembiochem. 2016 Feb 19. doi: 10.1002/cbic.201500564. [Epub ahead of print]
Targeted silver nanoparticles for ratiometric cell phenotyping.
Willmore AA, Simón-Gracia L, Toome K, Paiste P, Kotamraju VR, Mölder T, Sugahara KN, Ruoslahti E, Vraun GB, Teesalu T
Nanoscale. 2015 Dec 8. [Epub ahead of pront]
Ultrasound molecular imaging of tumor angiogenesis with a neuropilin-1-targeted microbubble.
Zhang H, Tam S, Ingham ES, Mahakian LM, Lai CY, Tumbale SK, Teesalu T, Hubbard NE, Borowsky AD, Ferrara KW
Biomaterials. 2015 Jul;56:104-13. doi: 10.1016/j.biomaterials.2015.03.043. Epub 2015 Apr 16.
A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis
Sugahara KN, Scodeller P, Braun GB, de mendoza TH, Yamazaki CM, luger MD, Kitayama J, Alvarez E, Howell SB, Teesalu T, Ruoslahti E, Lowy AM
J Control Release. 2015 Jun 11;212:59-69. doi: 10.1016/j.jconrel.2015.06.009. [Epub ahead of print]
An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability
Pang HB, Braun GB, Friman T, Aza-Blanc P, Ruidiaz ME, Sugahara KN, Teesalu T, Ruoslahti E.
Nat Commun. 2014 Oct 3;5:4904. doi: 10.1038/ncomms5904.
